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  • OPES and Implementation in Toy Model

    A practical guide to On-the-fly Probability Enhanced Sampling (OPES) with implementation details and a toy model demonstration.

    27 min read   ·   November 06, 2025

    2025   ·   Simulation   Sampling   MD   ·   Academic

  • Collective Variables and Free Energy Profile

    Understanding collective variables (CVs) and how to estimate free energy profiles from molecular simulations using kernel density estimation.

    4 min read   ·   November 03, 2025

    2025   ·   Simulation   Sampling   MD   ·   Academic

  • Reweighting Technique in Molecular Simulations: From Umbrella Sampling to MBAR

    An introduction to importance sampling and reweighting techniques in molecular simulations, covering umbrella sampling and MBAR (Multistate Bennett Acceptance Ratio).

    11 min read   ·   October 01, 2025

    2025   ·   Simulation   Math   Sampling   MD   ·   Academic

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